Having just updated windows 10, which I think updated the ASP.NET components to 4.8/or an update to 4.8, I suddenly started getting Http Error 500’s on every site on localhost, which is a problem for a web developer!
I went into Internet options and turned off Show friendly Http Error Messages, which then showed me it was a 500.19 error.
The answer was to go into Windows Features and ensure that Http Activation was turned on.
This post explained it for me, kind of.
https://stackoverflow.com/questions/20048486/http-error-500-19-and-error-code-0x80070021
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